Formalin-Fixed Paraffin Embedded (FFPE)

US Biolab’s extensive and diverse collection of archival FFPE samples include a wide range from normal, healthy tissues to rare disease, and oncology samples. Each sample undergoes rigorous review and analysis by our staff pathologists to ensure every tissue sample is viable and of adequate quantity for your assays. We have cultivated strong partnerships with hundreds of laboratories and hospitals worldwide, providing an unparalleled representation of indications from diverse demographics and indications. Our on-site histology lab enables us to maintain the highest levels of quality control and unique characterizations, ensuring your study has the curated, pathologist-verified samples you need to meet your high standards. Custom collections and samples can be developed based on your unique requirements. Please see our Custom Collections page for more information. Each sample is reviewed, selected, and annotated by a board-certified pathologist to support reliable results.

FFPE features may include

Tumor and normal adjacent tissue

It is a long established fact that a reader will be distracted by the readable content

Disease state and normal tissue

It is a long established fact that a reader will be distracted by the readable content

Blocks or sections

It is a long established fact that a reader will be distracted by the readable content

Associated clinical data

It is a long established fact that a reader will be distracted by the readable content

Storage maintained

It is a long established fact that a reader will be distracted by the readable content

Underrepresented populations

It is a long established fact that a reader will be distracted by the readable content

Guide and Data

Featured Resources

Discover valuable insights, expert guides, and essential protocols designed to support your research with high-quality biospecimens. 

Histology

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IHC and Validation Services

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FISH/ISH

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The  Process

Our FFPE Tissue Preparation Process

Discover valuable insights, expert guides, and essential protocols designed to support your research with high-quality biospecimens. 

Custom or prospective samples are available on request. Our supply chain is managed to the highest standards with white-glove logistics to ensure quality and reliability.

Reach out to us directly to inquire about specimen availability and project feasibility.

Ensuring Every Sample Counts

Our Quality Control Standards

Our rigorous validation process guarantees reliable results for both clinical and research applications. 

Pathology review for diagnosis verification

Sample integrity and tissue quality assessment

H&E staining and microscopic evaluation

Tumor percentage, necrosis, and cellularity annotation

Strict SOPs for handling and storage

Available molecular profiling data (where applicable)

Key Advantages of FFPE Specimens

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Long-term storage stability with preserved histological architecture

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Extensive availability (many clinical archives use FFPE)

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Compatibility with IHC, slide imaging, and molecular techniques

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Enables retrospective studies with well-annotated samples

Because FFPE blocks are widely archived in pathology labs, they are a rich resource for retrospective translational studies—especially in oncology.

Challenges & Solutions

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DNA/RNA degradation over time

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Chemical crosslinking may affect molecular analysis

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Sample quality variation across archives

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Requires optimized extraction protocols

With optimized processing techniques, many of these challenges can be minimized.

Featured Resources

Explore Insights and Research Tools

Discover valuable insights, expert guides, and essential protocols designed to support your research with high-quality biospecimens. 

Advancing Precision Research with FFPE Data

Discover how FFPE specimens enable molecular-level insights and reproducible results across oncology and translational studies.

Selecting the Right Specimens for Your Study

Explore our detailed catalogs and data sheets designed to simplify sample selection and ensure research accuracy.

Innovations in Biospecimen Preservation

Read about the latest breakthroughs and best practices improving the quality and longevity of FFPE tissue samples.

Frequently Asked Questions

Common questions about our fresh frozen and OCT tissue specimens

Can I get whole slides or serial sections?

Yes, you can request serial sections or full slides subject to availability of remaining material.

Do you provide molecular profiling?

Yes, you can request serial sections or full slides subject to availability of remaining material.

What is the age limit for FFPE blocks you accept?

Yes, you can request serial sections or full slides subject to availability of remaining material.

Are samples anonymized / de-identified?

Yes, you can request serial sections or full slides subject to availability of remaining material.

What if my target indication is not in inventory?

Yes, you can request serial sections or full slides subject to availability of remaining material.

At US Biolab, we are dedicated to advancing biomedical discovery by providing access to ethically sourced, clinically annotated human biospecimens.

Compliance

IRB-approved, ethically sourced specimens

Quality Assurance

Pathology reports & clinical data available

Global Access

Samples shipped worldwide in compliance with regulations

Scientific Support

Speak with our biospecimen specialists for custom requests