Widely used in gene and cell research, ISH and related FISH testing have revolutionized many areas of diagnostic medicine, with applications in oncology, preventative, and reproductive medicine.
FISH is the method of choice for detecting gene abnormalities and malignant cells with chromosomal rearrangements. Recent optimizations to the FISH process, particularly, have enabled microfluidic processing, significantly reducing reagent use and assay time. The process is adaptable to high-throughput environments, supporting remarkable innovation in disease detection.
Fluorescence in Situ Hybridization (FISH) Capabilities
Supporting cytogenetic abnormality detection in individual cells.
Genetic Abnormalities
Genetic abnormalities that FISH can detect include insertions, deletions, amplifications, fusions, and translocations.
Disease-specific FISH assays are available. Please speak to us about your study.
Sample Types
Sample types that can be used in FISH assays include:
Blood
CTCs
CECs
FFPE
Bone
Cell lines
Fresh and frozen tissue
In Situ Hybridization (ISH) Capabilities
Highly sensitive gene expression measurement with spatial context: single-plex, multi-plex, and dual ISH-ICH. Like FISH, ISH can examine RNA localization and specific gene expression at the cellular level. Targets can be commercially supplied or customized to your study’s needs.
Genetic abnormalities that FISH can detect include insertions, deletions, amplifications, fusions, and translocations.
Sample Types
Sample types that can be used in ISH assays include:
Collaborate with US
FISH and ISH assays are suitable for both clinical and preclinical research, and are scalable to meet your specific needs.
Our team works closely with yours to ensure the right strategies are applied to achieve the results you want.
At US Biolab, we are dedicated to advancing biomedical discovery by providing access to ethically sourced, clinically annotated human biospecimens.
Compliance
IRB-approved, ethically sourced specimens
Quality Assurance
Pathology reports & clinical data available
Global Access
Samples shipped worldwide in compliance with regulations
Scientific Support
Speak with our biospecimen specialists for custom requests